支气管哮喘的诊断和治疗.pptx
- dididadade个人认证 |
- 2021-04-20 发布|
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- 89页
支气管哮喘的诊断和治疗;邓丽君
1953~1995
因哮喘急性发作
病逝泰国;由于哮喘和束手无策的医生而死于维也纳;内 容;流行病学;中国哮喘疾病的死亡率最高:;内 容;是一种慢性的气道炎症
由多种细胞(嗜酸性粒细胞、肥大细胞、T淋巴细胞、中性粒细胞、气道上皮细胞等)及细胞组分共同参与
慢性炎症导致气道高反应性的增加,通常出现广泛多变的可逆性气流受限,并引起反复发作性的喘息、气急、胸闷或咳嗽等症状,常在夜间和清晨发作、加剧
多数患者可自行缓解或经治疗缓解;哮喘病人;Figure 1. Specimen of Bronchial Mucosa from a Subject without Asthma (Panel A) and a Patient with Mild Asthma (Panel B) (Hematoxylin and Eosin, x40).
In the subject without asthma, the epithelium is intact; there is no thickening of the sub-basement membrane, and there is no cellular infiltrate. In contrast, in the patient with mild asthma, there is evidence of goblet-cell hyperplasia in the epithelial-cell lining. The sub-basement membrane is thickened, with collagen deposition in the submucosal area, and there is a cellular infiltrate. Photographs courtesy