衣被蛋白基因的克隆及其在病毒增殖中的表达分析.docx

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中国医学科学院北京协和医学院硕士研究生学位论文Abstract

中国医学科学院北京协和医学院硕士研究生学位论文

Abstract

Herpes simplex virus(HSV)is a common pathogen that is harmful to human health． HSV is divided into two serotypes：HSV-1 and HSV-2．HSV infect host through the damaged skin or mucous membrane and proliferate in epithelial tissue．On the other hand， HSV even infects neurons of nerve terminal situated in epithelial tissue．After primary infection，the virus could establish latent infection at trigeminal ganglion and dorsal root ganglion etc．The herpes simplex virus I type(herpes simplex virus I，HSV-1)Can infect skin，mucous membrane and nervous system and lead to disease such as keratitis，herpes encephalitis，herpes labialis and gingivostomatitis．

Tegument protein are structure protein，also acting as critical protein for viru

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